The following research studies were funded in whole or in part by the Alvin Grancell/Mary Burns Chair for Rehabilitation Sciences Research. Richard Casaburi, PhD, MD, and President of PERF, holds the chair.
21st century perspective on chronic obstructive pulmonary disease
Ward SA, Casaburi R. Respiration 2001; 68: 557-561.
Effect of hyperoxia on gas exchange and lactate kinetics following exercise onset in nonhypoxemic COPD patients
Somfay A, Pórszász J, Lee S-M, Casaburi R. Chest 2002; 121: 393-400.
Long-term effects of a maintenance program after supervised or self-monitored training programs in patients with COPD
Puente-Maestu L, Sanz ML, Sanz P, de Oña RJ, Arnedillo A, Casaburi R. Lung 2003; 181: 67-78.
Testosterone dose-dependently increases maximal voluntary strength and leg power, but does not affect fatigability or specific tension
Storer TW, Magliano L, Woodhouse L, Lee ML, Dzekov C, Dzekov J, Casaburi R, Bhasin S.. The Journal of Clinical Endocrinology & Metabolism 2003; 88: 1478-1485.
Effects of testosterone and resistance training in men with chronic obstructive pulmonary disease
Casaburi R, Bhasin S, Cosentino L, Porszasz J, Somfay A, Lewis MI, Fournier M, Storer TW. American Journal of Respiratory and Critical Care Medicine 2004; 170: 870-878.
Older men are as responsive as young men to the anabolic effects of graded doses of testosterone on the skeletal muscle
Bhasin S, Woodhouse L, Casaburi R, Singh AB, Mac RP, Lee M, Yarasheski KE, Sinha-Hikim I, Dzekov C, Dzekov J. The Journal of Clinical Endocrinology & Metabolism 2005; 90: 678-688.
Factors determining constant work rate exercise tolerance in COPD and their role in dictating the minimal clinically important difference in response to interventions
Casaburi R. COPD: Journal of Chronic Obstructive Pulmonary Disease 2005; 2: 131-136.
Improvement in exercise tolerance with the combination of tiotropium and pulmonary rehabilitation in patients with COPD
Casaburi R, Kukafka D, Cooper CB, Witek Jr TJ, Kesten S. Chest 2005; 127: 809-817.
Dose-dependent effects of testosterone on sexual function, mood, and visuospatial cognition in older men
Gray PB, Singh AB, Woodhouse LJ, Storer TW, Casaburi R, Dzekov J, Dzekov C, Sinha-Hikim I, Bhasin S. The Journal of Clinical Endocrinology & Metabolism 2005; 90: 3838-3846.
Endurance exercise training during haemodialysis improves strength, power, fatigability and physical performance in maintenance haemodialysis patients
Storer TW, Casaburi R, Sawelson S, Kopple JD. Nephrology Dialysis Transplantation 2005; 20: 1429-1437.
Pulmonary rehabilitation in chronic obstructive pulmonary disease
Troosters T, Casaburi R, Gosselink R, Decramer M. American Journal of Respiratory and Critical Care Medicine 2005; 172: 19-38.
Combination therapy for exercise intolerance in COPD
Casaburi R. BMJ Publishing Group Ltd; 2006.
Getting Serious About Strength Training
Casaburi R. LWW; 2006.
Activity monitoring in assessing activities of daily living
Casaburi R. COPD: Journal of Chronic Obstructive Pulmonary Disease 2007; 4: 251-255.
Supervised high intensity continuous and interval training vs. self-paced training in COPD
Varga J, Porszasz J, Boda K, Casaburi R, Somfay A. Respiratory Medicine 2007; 101: 2297-2304.
Pulmonary rehabilitation for management of chronic obstructive pulmonary disease
Casaburi R, ZuWallack R. New England Journal of Medicine 2009; 360: 1329-1335.
Physiologic responses to linear treadmill and cycle ergometer exercise in COPD
Hsia D, Casaburi R, Pradhan A, Torres E, Porszasz J. European Respiratory Journal 2009.
Breath-by-breath quantification of progressive airflow limitation during exercise in COPD: a new method
Ma S, Hecht A, Varga J, Rambod M, Morford S, Goto S, Casaburi R, Porszasz J. Respiratory Medicine 2010; 104: 389-396.
Aclidinium bromide improves exercise endurance and lung hyperinflation in patients with moderate to severe COPD
Maltais F, Celli B, Casaburi R, Porszasz J, Jarreta D, Seoane B, Caracta C. Respiratory Medicine 2011; 105: 580-587.
Testosterone and resistance training effects on muscle nitric oxide synthase isoforms in COPD men
Chavoshan B, Fournier M, Lewis MI, Porszasz J, Storer TW, Da X, Rambod M, Casaburi R. Respiratory Medicine 2012; 106: 269-275.
Exhaled breath condensates: analyzing the expiratory plume
Effros RM, Casaburi R, Porszasz J, Morales EM, Rehan V. American Journal of Respiratory and Critical Care Medicine 2012; 185: 803-804.
Comment on ‘The effect of temperature on exhaled breath condensate collection’
Effros RM, Casaburi R, Porszasz J, Morales EM, Saraswat A, Rehan V. Journal of Breath Research 2012; 6: 048001.
Cardiopulmonary exercise testing: does it improve perioperative care and outcome?
Stringer W, Casaburi R, Older P. Current Opinion in Anesthesiology 2012; 25: 178-184.
Physiologic effects of an ambulatory ventilation system in chronic obstructive pulmonary disease
Porszasz J, Cao R, Morishige R, van Eykern LA, Stenzler A, Casaburi R. American Journal of Respiratory and Critical Care Medicine 2013; 188: 334-342.
Instantaneous quantification of skeletal muscle activation, power production, and fatigue during cycle ergometry
Coelho AC, Cannon DT, Cao R, Porszasz J, Casaburi R, Knorst MM, Rossiter HB. Journal of Applied Physiology 2014; 118: 646-654.
An official American Thoracic Society/European Respiratory Society statement: update on limb muscle dysfunction in chronic obstructive pulmonary disease
Maltais F, Decramer M, Casaburi R, Barreiro E, Burelle Y, Debigare R, Dekhuijzen PR, Franssen F, Gayan-Ramirez G, Gea J. American Journal of Respiratory and Critical Care Medicine 2014; 189: e15-e62.
Selecting constant work rates for endurance testing in COPD: the role of the power-duration relationship
van der Vaart H, Murgatroyd SR, Rossiter HB, Chen C, Casaburi R, Porszasz J. COPD: Journal of Chronic Obstructive Pulmonary Disease 2014; 11: 267-276.
Effect of endurance and/or strength training on muscle fiber size, oxidative capacity, and capillarity in hemodialysis patients
Lewis MI, Fournier M, Wang H, Storer TW, Casaburi R, Kopple JD. Journal of Applied Physiology 2015; 119: 865-871.
The 6-minute-walk distance test as a chronic obstructive pulmonary disease stratification tool. Insights from the COPD Biomarker Qualification Consortium
Celli B, Tetzlaff K, Criner G, Polkey MI, Sciurba F, Casaburi R, Tal-Singer R, Kawata A, Merrill D, Rennard S. American Journal of Respiratory and Critical Care Medicine 2016; 194: 1483-1493.
Skeletal muscle power and fatigue at the tolerable limit of ramp-incremental exercise in COPD
Cannon DT, Coelho AC, Cao R, Cheng A, Porszasz J, Casaburi R, Rossiter HB. Journal of Applied Physiology 2016; 121: 1365-1373.
Exercise, ageing and the lung
Roman MA, Rossiter HB, Casaburi R. European Respiratory Journal 2016: ERJ-00347-02016.
A novel spirometric measure identifies mild COPD unidentified by standard criteria
Dilektasli AG, Porszasz J, Casaburi R, Stringer WW, Bhatt SP, Pak Y, Rossiter HB, Washko G, Castaldi PJ, Estepar RSJ. Chest 2016; 150: 1080-1090.
Reliability and Physiological Interpretation of Pulmonary Gas Exchange by “Circulatory Equivalents” in Chronic Heart Failure
Tan C, Rossiter HB, Porszasz J, Bowen TS, Witte KK, Stringer WW, Casaburi R, Hansen JE. Journal of the American Heart Association 2018; 7: e008072.